Santa Cruz Vacation Packages
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Your Santa Cruz Vacation
There's no better way to get away than with one of our vacation packages to Santa Cruz. The lively atmosphere and beaches are two of the countless reasons to spend some time in this awesome city. A trip to Santa Cruz is an ideal opportunity to do some sightseeing. Be sure to stop by renowned attractions like Lapostolle Clos Apalta Winery, Laura Hartwig Winery and Casino Colchagua. Your perfect Santa Cruz vacation is a couple of clicks away. Browse airfares, hotels and more on Expedia for an adventure that's tailored just for you.
Top Santa Cruz Vacation Deals
Price found within the past 48 hours. Click for updated prices.
Ready to book your vacation to Santa Cruz?
Santa Cruz Hotel Deals
Santa Cruz Plaza
Plaza De Armas 286 Santa Cruz O'Higgins
Fully refundableReserve now, pay when you stay
CA $164
CA $164 total
Oct 18 - Oct 19
8.8/10 Excellent! (373 reviews)
"El hotel ya está muy viejo, tiene buenas instalaciones y el spa está bien pero las habitaciones ocupan renovación, sobre todo alfombras y aire acondicionado."
Reviewed on Sep 26, 2026
Hotel Cava Colchagua
Barreales´s Way Santa Cruz O'Higgins
Fully refundableReserve now, pay when you stay
CA $206
CA $206 total
Oct 28 - Oct 29
9/10 Wonderful! (177 reviews)
"Excelente y original experiencia boutique Una propuesta realmente innovadora. Se trata de un hotel boutique hermoso cuyas habitaciones están acondicionadas dentro de barricas de roble, muy bien adaptadas y acogedoras. Como sugerencia de mejora, creo que a las habitaciones más grandes les vendría ..."
Reviewed on Aug 7, 2026
Hotel Boutique Vendimia Premium
Ismael Valdes 92 Santa Cruz O'Higgins
Fully refundableReserve now, pay when you stay
CA $80
CA $80 total
Oct 6 - Oct 7
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Stay near popular Santa Cruz attractions
Lapostolle Clos Apalta Winery
9.4/10 (21 reviews)
You can enjoy a tasting or tour at Lapostolle Clos Apalta Winery during your travels to Santa Cruz. While in this relaxing area, you can savor the wineries and restaurants.
Casino Colchagua
8.0/10 (6 reviews)
Why not roll the dice with a visit to Casino Colchagua during your visit to Santa Cruz? While in this relaxing area, you can savor the wineries and restaurants.
Colchagua Campo y Vino
9.4/10 (3 reviews)
Enjoy an outing to Colchagua Campo y Vino during your stay in Santa Cruz. While in this relaxing area, you can savor the wineries and restaurants.
Laura Hartwig Winery
9.0/10 (17 reviews)
You can enjoy a tasting or tour at Laura Hartwig Winery during your travels to Santa Cruz. While in this relaxing area, you can savor the wineries and restaurants.
Bodega Viña Viu Manent
10.0/10 (1 review)
You can enjoy a tasting or tour at Bodega Viña Viu Manent during your travels to Santa Cruz. While in this relaxing area, you can savor the wineries and restaurants.
Museo de Colchagua
9.6/10 (24 reviews)
You can spend time exploring the galleries in Museo de Colchagua during your trip to Santa Cruz. While in this relaxing area, you can savor the wineries and restaurants.
Plaza de Armas
8.2/10 (34 reviews)
Find out about the history of Santa Cruz when you spend time at Plaza de Armas. While in this relaxing area, you can savor the wineries and restaurants.
What to do in Santa Cruz
Frequently asked questions
How much does a Santa Cruz vacation package cost?
You can pick up a vacation package to this popular destination from CA $910 on Expedia. However, how much your vacation to Santa Cruz costs will depend on the length of stay, season and hotel choice.
What are the cheapest months to go to Santa Cruz?
You can usually find lower rates and better availability in May, July and September. Check out our cheap Santa Cruz vacation packages and you could land some excellent off-season deals.
How many days is enough for Santa Cruz?
Usually, a handful of days is enough for a Santa Cruz vacation. With a carefully crafted itinerary, you can visit all the leading attractions such as Laura Hartwig Winery, as well as explore some hidden treasures along the way.
Is it worth booking a vacation package to Santa Cruz?
Santa Cruz has everything you need for the perfect break — history, culture and festivals are just the start. Whether you want to visit sights like Plaza de Armas and Museo de Colchagua, or take the path less travelled, you'll have plenty to explore on your Santa Cruz vacation.
How to find the best Santa Cruz package deals?
Use Expedia's filters to help you find some of the best Santa Cruz package deals. When you begin your search, just set your maximum budget and then sort the results by "Price: low to high." If you want to save, plan your trip for midweek, or look for Santa Cruz package deals in the off-peak season. Switch up your travel dates and you may land even better discounts. As a rule of thumb, it's usually best to lock in your vacation package as soon as possible.
Is it cheaper to book a Santa Cruz vacation as a package?
Expedia vacation packages are designed to help you keep more money in your pocket. Bundle your hotel, car rental and flight into one great-value price and you could save hundreds of dollars. You'll usually get a better deal than booking each component separately. And you'll still get the flexibility to create a customized Santa Cruz vacation by choosing your preferred accommodation type, airline and car class.
When to book a vacation package to Santa Cruz?
If you've got your Santa Cruz travel dates locked in, book as early as you can to score some fantastic deals. With Expedia, you can often reserve some flights up to one year in advance. Prefer spur-of-the-moment adventures? Our last-minute deals are ideal for setting off on a whim.
How to plan a trip to Santa Cruz?
- Pick the right time to travel: Your schedule, preferred season and the type of weather you enjoy can all impact your decision on when to go to Santa Cruz.
- Calculate your budget: Ensure you have enough money to cover everything from transportation and food to airfares and activities. Your hotel will likely be the biggest expense during your trip to Santa Cruz.
- Work out your trip length: Think about how long you'd like to spend exploring Santa Cruz. Plan your itinerary so you can get to all the attractions and activities you're interested in at a comfortable pace.
- Bundle your airfare and accommodations: Once you've nailed down your dates and duration, lock in the right Santa Cruz vacation package for you.
Explore a world of travel with Expedia
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- Hotel Boutique Santa Teresita
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
